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NEW YORK DAWN™ > Blog > Health > 3D-printed biodressing capabilities throughout a number of phases of therapy for continual wounds and extreme burns
3D-printed biodressing capabilities throughout a number of phases of therapy for continual wounds and extreme burns
Health

3D-printed biodressing capabilities throughout a number of phases of therapy for continual wounds and extreme burns

Last updated: June 10, 2025 3:06 am
Editorial Board Published June 10, 2025
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The gear permits the dressing to be made exactly and the mesenchymal cells to be appropriately distributed all through the hydrogel, maintaining them viable throughout bioprinting and use. Credit score: In Situ

In Brazil, there’s nonetheless no superior remedy product for the therapy of continual wounds and burns that has been registered with well being regulatory our bodies. A startup based mostly on the Supera Innovation and Expertise Park in Ribeirão Preto, within the inside of the state of São Paulo, intends to interrupt down this barrier and change into a pioneer on this phase.

The corporate has developed a 3D-printed biodressing containing human umbilical twine stem cells for the therapy of sufferers with continual wounds and extreme burns.

In Situ will current its know-how on the College of São Paulo (USP) stand on the worldwide VivaTech truthful, one in all Europe’s largest startup and know-how occasions, which takes place June 11–14 in Paris, France.

“Participating in VivaTech represents an excellent opportunity for us to understand how the market for advanced therapy products works in Europe, where there are already some registered products,” Adriana Manfiolli, a researcher and associate within the firm, advised Agência FAPESP.

Named Mensencure, the biodressing is made with hydrogel and accommodates mesenchymal cells, which secrete quite a few bioactive molecules with completely different capabilities within the therapeutic course of, resembling cytokines and progress components answerable for immunomodulation, angiogenesis (the creation of recent blood vessels) and bettering the standard of scar tissue.

The 3D biodressing is taken into account good as a result of it accommodates residing cells that may understand the indicators emitted by pores and skin accidents and reply by releasing cytokines and progress components based on the tissue’s wants. Not like most typical merchandise, which solely intention to cowl the lesion or deal with a selected part of therapeutic, Mensencure acts within the completely different phases of pores and skin therapeutic.

Pores and skin lesions in diabetics

One of many product’s purposes is the therapy of pores and skin lesions in individuals with sort 1 diabetes, who’ve problem therapeutic their pores and skin. When the illness just isn’t properly managed, an extra of sugar within the bloodstream hinders varied levels of therapeutic and prevents tissue regeneration.

“We know that the skin is a fabulous tissue that heals naturally, but there are people with underlying pathologies, such as diabetes, in whom this process is impaired. The biodressing is intended precisely for these patients with impaired healing, whose wounds don’t close or sometimes take months or even years to heal,” says Oliveira.

Nonetheless, the corporate intends to make use of the biodressing initially to deal with sufferers with stress accidents, popularly often called bedsores. Medical trials are nonetheless wanted, although. If the outcomes are constructive, the corporate can request approval for the product from the Nationwide Well being Surveillance Company (ANVISA), the federal company that regulates well being therapies, applied sciences, and procedures in Brazil.

“We’re in the midst of this critical period, working on the production of both the cells and the dressing in accordance with Good Manufacturing Practices [GMP] in order to obtain authorization from ANVISA to carry out a clinical study,” says Oliveira.

The researchers’ aim is to supply the biodressing and different merchandise based mostly on the know-how within the firm’s laboratory. “Unlike most biotechs, we want to go to market,” she says.

Quotation:
3D-printed biodressing capabilities throughout a number of phases of therapy for continual wounds and extreme burns (2025, June 9)
retrieved 9 June 2025
from https://medicalxpress.com/information/2025-06-3d-biodressing-functions-multiple-phases.html

This doc is topic to copyright. Other than any truthful dealing for the aim of personal research or analysis, no
half could also be reproduced with out the written permission. The content material is supplied for info functions solely.

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