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New analysis in Diabetes, Weight problems and Metabolism reveals that metformin, a medicine historically prescribed to deal with diabetes, is linked to decrease dangers of dementia and early demise.
Within the examine by investigators at Taipei Medical College that included 452,777 adults with various levels of obese and weight problems, 35,784 instances of dementia and 76,048 deaths occurred over 10 years. Metformin customers exhibited considerably decrease dangers of each dementia and all-cause demise than nonusers.
The advantages of metformin have been seen throughout all classes of obese, weight problems, and extreme weight problems, with 8–12% decrease dangers of dementia and 26–28% decrease dangers of demise.
“Although our study results are promising for metformin’s effects on dementia and mortality, further research is required to explore the mechanisms involved,” stated co-corresponding writer Chiehfeng Chen, MD, Ph.D., MPH.
Extra data:
Protecting Impact of Metformin Towards Dementia in Sufferers With Weight problems: Outcomes From a World Federated Well being Community Evaluation, Diabetes Weight problems and Metabolism (2025). DOI: 10.1111/dom.16647
Quotation:
A diabetes drug might assist forestall dementia (2025, August 6)
retrieved 6 August 2025
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