For sufferers with cardiac arrest and a shockable rhythm, automated exterior defibrillators (AEDs) in non-public houses enhance outcomes however can’t be thought-about cost-effective at present pricing, in response to a research printed on-line Oct. 25 in JAMA Inner Medication to coincide with the European Resuscitation Council Congress, held from Oct. 23 to 25 in Rotterdam, Netherlands.
Lars W. Andersen, M.D., M.P.H., Ph.D., from Aarhus College in Denmark, and colleagues examined the effectiveness of AEDs when used for cardiac arrests in non-public houses in a cohort research utilizing observational knowledge from the Cardiac Arrest Registry to Improve Survival in the US from January 2017 to December 2024. To find out the causal relationship between AED utility and survival to hospital discharge, a difference-in-difference strategy was used.
The evaluation included 582,536 sufferers (61.8% male) with a median age of 65 years. The researchers discovered that amongst sufferers with a shockable rhythm, survival was higher with AED utility in contrast with no AED utility (threat ratio, 1.26), however not in sufferers with a nonshockable rhythm. Within the difference-in-difference evaluation, outcomes have been constant.
For an AED in a non-public house, the incremental cost-effectiveness ratio was $4,481,659 per quality-adjusted life-year. AEDs in non-public houses can be thought-about cost-effective at a yearly cardiac arrest incidence per particular person above 1.3% or at an AED value lower than $65 at a cost-effectiveness threshold of $200,000 per quality-adjusted life-year.
“The indiscriminate purchase of AEDs for individual private homes cannot be considered cost-effective at the current pricing of AEDs,” the authors write.
Extra info:
Lars W. Andersen et al, Effectiveness and Value-Effectiveness of Automated Exterior Defibrillators in Non-public Properties, JAMA Inner Medication (2025). DOI: 10.1001/jamainternmed.2025.6123More Info
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