Dr. Robert Stevens, chief of the Division of Informatics, Integration and Innovation at Johns Hopkins Drugs, observes an electrocardiogram monitor. Stevens’ staff used synthetic intelligence to extract beforehand undetected indicators in these routine coronary heart checks that strongly predict which sufferers will endure doubtlessly lethal issues after surgical procedure. Credit score: Will Kirk/Johns Hopkins College
A brand new synthetic intelligence mannequin discovered beforehand undetected indicators in routine coronary heart checks that strongly predict which sufferers will endure doubtlessly lethal issues after surgical procedure. The mannequin considerably outperformed threat scores at present relied upon by docs.
The work by Johns Hopkins College researchers, which turns customary and cheap check outcomes right into a doubtlessly life-saving instrument, may remodel decision-making and threat calculation for each sufferers and surgeons.
“We demonstrate that a basic electrocardiogram contains important prognostic information not identifiable by the naked eye,” stated senior creator Robert D. Stevens, chief of the Division of Informatics, Integration and Innovation at Johns Hopkins Drugs. “We can only extract it with machine learning techniques.”
The findings are revealed within the British Journal of Anaesthesia.
A considerable portion of individuals develop life-threatening issues after main surgical procedure. The chance scores relied upon by docs to establish who’s in danger for issues are solely correct in about 60% of instances.
Hoping to create a extra correct technique to predict these well being dangers, the Johns Hopkins staff turned to the electrocardiogram (ECG), an ordinary, pre-surgical coronary heart check extensively obtained earlier than main surgical procedure. It is a quick, noninvasive technique to consider cardiac exercise by electrical indicators, and it may sign coronary heart illness.
However ECG indicators additionally decide up on different, extra refined physiological data, Stevens stated, and the Hopkins staff suspected they may discover a treasure trove of wealthy predictive information—if AI may assist them see it.
“The ECG contains a lot of really interesting information not just about the heart but about the cardiovascular system,” Stevens stated.
“Inflammation, the endocrine system, metabolism, fluids, electrolytes— all of these factors shape the morphology of the ECG. If we could get a really big dataset of ECG results and analyze it with deep learning, we reasoned we could get valuable information not currently available to clinicians.”

Synthetic intelligence can extract beforehand undetected indicators in fundamental electrocardiograms, routine coronary heart checks, that strongly predict which sufferers will endure doubtlessly lethal issues after surgical procedure. Credit score: Will Kirk/Johns Hopkins College
The staff analyzed preoperative ECG information from 37,000 sufferers who had surgical procedure at Beth Israel Deaconess Medical Heart in Boston.
The staff skilled two AI fashions to establish sufferers more likely to have a coronary heart assault, a stroke, or die inside 30 days after their surgical procedure. One mannequin was skilled on simply ECG information. The opposite, which the staff known as a “fusion” mannequin, mixed the ECG data with extra particulars from affected person medical information akin to age, gender, and current medical circumstances.
The ECG-only mannequin predicted issues higher than present threat scores, however the fusion mannequin was even higher, capable of predict which sufferers would endure post-surgical issues with 85% accuracy.
“Surprising that we can take this routine diagnostic, this 10 seconds worth of data, and predict really well if someone will die after surgery,” stated lead creator Carl Harris, a Ph.D. pupil in biomedical engineering. “We have a really meaningful finding that can improve the assessment of surgical risk.”
The staff additionally developed a technique to elucidate which ECG options may be related to a coronary heart assault or a stroke after an operation.
“You can imagine if you’re undergoing major surgery, instead of just having your ECG put in your records where no one will look at it, it’s run thru a model and you get a risk assessment and can talk with your doctor about the risks and benefits of surgery,” Stevens stated.
“It’s a transformative step forward in how we assess risk for patients.”
Subsequent, the staff will additional check the mannequin on datasets from extra sufferers. They’d additionally like to check the mannequin prospectively with sufferers about to endure surgical procedure.
The staff would additionally like to find out what different data may be extracted from ECG outcomes by AI.
Extra data:
British Journal of Anaesthesia (2025).
Offered by
Johns Hopkins College
Quotation:
AI can predict issues from surgical procedure higher than docs (2025, September 17)
retrieved 17 September 2025
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