Personalization of the hemoglobin app results in improved efficiency in the actual world throughout the examined Hgb vary. Credit score: Proceedings of the Nationwide Academy of Sciences (2025). DOI: 10.1073/pnas.2424677122
Anemia impacts greater than 2 billion individuals worldwide, together with an estimated 83 million People at excessive threat. Now, a brand new app delivers dependable, accessible screening on to customers.
A brand new examine co-authored by Chapman College professor and founding dean of the Fowler Faculty of Engineering, Dr. L. Andrew Lyon, unveils a significant development in noninvasive well being know-how: a smartphone app that makes use of synthetic intelligence and a photograph of a person’s fingernail to detect anemia.
Printed within the Proceedings of the Nationwide Academy of Sciences, the examine demonstrates that this noninvasive, AI-augmented app offers hemoglobin estimates that rival conventional lab testing. With greater than 1.4 million assessments carried out by greater than 200,000 customers, the app represents a scalable, low-cost answer that broadens entry to anemia screening, particularly in underserved and distant communities.
With elevated entry, this app brings dependable screening instantly into the palms of customers, enabling real-time well being monitoring and earlier intervention, empowering customers to make knowledgeable choices with out ready for lab outcomes. Whereas not meant for self-diagnosis, the app helps customers perceive when to seek the advice of a well being care supplier.
The app is especially invaluable for these with power anemia, similar to individuals with kidney illness or most cancers, who typically require frequent monitoring. The examine confirmed that personalised app use in these sufferers improved accuracy by almost 50%, enabling safer, simpler at-home administration. As well as, geolocation information enabled the primary county-level anemia prevalence map within the U.S.
Particularly, app personalization for power anemia sufferers improved accuracy (from ±1.36 to ±0.74 g/dL). Hemoglobin (Hgb) estimates confirmed a imply absolute error of ±0.72 g/dL, enhancing to ±0.50 g/dL in customers with Hgb >10 g/dL.
“This research, more than eight years in the making, represents a meaningful step toward improving accessibility in health care,” mentioned Dr. Lyon. “It’s a testament to long-term collaboration and a commitment to empowering patients through innovation.”
Extra data:
Robert G. Mannino et al, Actual-world implementation of a noninvasive, AI-augmented, anemia-screening smartphone app and personalization for hemoglobin degree self-monitoring, Proceedings of the Nationwide Academy of Sciences (2025). DOI: 10.1073/pnas.2424677122
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AI-powered app permits anemia screening utilizing fingernail selfies (2025, Could 16)
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