Coronary artery illness (CAD) is frequent in sufferers with cirrhosis, however cirrhosis itself isn’t considerably related to an elevated CAD threat, in keeping with a assessment printed on-line Nov. 21 within the Journal of Scientific and Translational Hepatology.
Chunru Gu, from the Instructing Hospital of the China Medical College in Shenyang, and colleagues carried out a scientific assessment and meta-analysis to look at CAD incidence and prevalence in sufferers with and with out liver cirrhosis.
Based mostly on 51 included research, the researchers discovered that the pooled incidences of CAD, acute coronary syndromes, and myocardial infarction (MI) had been 2.28, 2.02, and 1.80%, respectively. There was no vital affiliation between liver cirrhosis and CAD incidence or MI.
The pooled prevalence charges of CAD, acute coronary syndromes, and MI had been 18.87, 12.54, and 6.12%, respectively. There was no vital affiliation between liver cirrhosis and CAD prevalence or MI. Nonalcoholic steatohepatitis, hepatitis C virus, superior age, male intercourse, diabetes mellitus, hypertension, hyperlipidemia, smoking historical past, and household historical past of CAD had been considerably related to CAD in sufferers with cirrhosis.
“Large-scale prospective studies are needed to clarify how to screen for and prevent CAD in the high-risk population with liver cirrhosis,” the authors write.
One writer reported being an editorial board member of the Journal of Scientific and Translational Hepatology.
Extra info:
Chunru Gu et al, Danger of Coronary Artery Illness in Sufferers with Liver Cirrhosis: A Systematic Overview and Meta-analysis, Journal of Scientific and Translational Hepatology (2024). DOI: 10.14218/JCTH.2024.00226
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