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Childhood mind tumor survival depends upon the kind of tumor. Evaluating survival charges throughout international locations is tough, as a result of mind tumors aren’t recorded in the identical manner all over the place in Europe. A brand new research led by the Princess Máxima Middle helps to vary that. For the primary time, the analysis gives a transparent and clinically related overview of survival outcomes for youngsters with mind tumors.
Researchers on the Princess Máxima Middle analyzed knowledge from greater than 30,000 youngsters identified with a mind tumor between 1998 and 2013. The info got here from 80 most cancers registries throughout 31 European international locations. The research was revealed at this time in The Lancet Oncology.
Aligned with scientific apply
The research focuses on the 4 most typical kinds of mind tumors in youngsters: low-grade gliomas, high-grade gliomas, ependymomas, and medulloblastomas. The researchers checked out each short- and long-term survival, in addition to the proportion of kids thought of cured. They used a brand new classification system that higher displays how docs diagnose and deal with mind tumors in apply.
“For this study, we restructured the tumor categories in the cancer registries to match how tumors are diagnosed today,” explains Dr. Raoull Hoogendijk, who labored on the research as a part of his Ph.D. analysis within the Karim-Kos and Van Vuurden analysis teams on the Máxima. “That means the numbers now align much better with clinical reality, and doctors can use them more effectively to compare outcomes.”
The place can we stand?
One key discovering is that variations in survival between international locations are smaller than beforehand thought. This means that youngsters throughout Europe typically have entry to related therapies. Between 1998 and 2013, survival charges for youngsters with mind tumors within the Netherlands have been about common in comparison with different European international locations—providing each reassurance and course for additional enchancment.
“This study shows us where we stand in Europe, and where there’s room to grow,” says Dr. Henrike Karim-Kos, analysis group chief on the Máxima and the Netherlands Complete Most cancers Group (IKNL), and coordinator of the research. “For policymakers, health care professionals, and researchers, this overview provides valuable insights to improve care and data registration. Together, we can work toward better outcomes for children with cancer.”
A basis for higher therapies
For the primary time, the research additionally maps out what number of youngsters will be thought of cured. These insights assist docs and researchers refine therapies—with the final word aim of curing all youngsters with most cancers, whereas preserving their high quality of life.
Prof. Eelco Hoving, Scientific Director of Neuro-oncology and pediatric neurosurgeon who additionally labored on the research, provides, “This study shows that survival rates for children with brain tumors have improved over the past 15 years. But survival for children with high-grade gliomas remains far too low. Our findings highlight the urgent need for better treatments for these—and all—children with brain tumors.”
Extra data:
Lengthy-term survival and remedy fraction estimates for paediatric central nervous system tumours in 31 European international locations (EUROCARE-6): a population-based research, The Lancet Oncology (2025).
Supplied by
Princess Máxima Middle for Pediatric Oncology
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Examine provides clearer image of childhood mind tumor survival (2025, July 28)
retrieved 28 July 2025
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