Excessive dietary inflammatory index (DII), which quantifies the inflammatory potential of food plan, is related to elevated prevalence of atopic dermatitis (AD), in line with a research revealed on-line June 19 in Frontiers of Immunology.
Kaiyue Tan, from The First Scientific School of Shandong College of Conventional Chinese language Medication in Jinan, China, and colleagues examined the affiliation between DII quartiles and AD threat utilizing large-scale population-based cross-sectional information from the Korean Nationwide Well being and Diet Examination Survey 2017 to 2023.
The researchers noticed a big affiliation between increased DII scores with AD prevalence. In comparison with these within the lowest quartile, contributors within the highest DII quartile had a considerably elevated threat of AD (adjusted odds ratio, 1.73), and there was a big intercourse interplay famous, with stronger associations seen within the feminine group. A potential linear affiliation was noticed between DII and AD threat in restricted cubic spline evaluation.
“This study demonstrated for the first time in an Asian population that high DII is positively associated with AD risk, and the effect was more pronounced in women and those ≤ 54 years of age,” the authors write. “Future validation of associations through repeated dietary measurements, inclusion of omitted anti-inflammatory components, and prospective designs is warranted.”
Extra info:
Kaiyue Tan et al, Dietary irritation: a possible driver of atopic dermatitis?–Proof from KNHANES 2017–2023, Frontiers in Immunology (2025). DOI: 10.3389/fimmu.2025.1606145
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