The Geriatric Dietary Danger Index (GNRI) is a dependable predictive marker for overactive bladder (OAB) within the aged, based on a research revealed on-line Feb. 10 in Frontiers in Vitamin.
Wei Zheng, from Hangzhou Medical School in China, and colleagues examined the affiliation between GNRI and the prevalence of OAB in a research involving 17,161 aged people from the Nationwide Well being and Vitamin Examination Survey between 2005 and 2018. Subgroup analyses have been used to evaluate influencing components, and the predictive utility of GNRI was examined. A mediation evaluation was performed to evaluate the affect of inflammatory response and cognitive perform on the interplay between GNRI and OAB.
The researchers discovered that GNRI was considerably decrease within the OAB group versus the non-OAB group. GNRI considerably predicted OAB in a multifactorial logistic regression evaluation. A nonlinear unfavorable correlation was seen between GNRI and the chance for OAB within the aged. GNRI outperformed serum albumin or physique mass index alone in predicting OAB threat in a receiver working attribute evaluation.
The connection between GNRI and OAB was mediated by inflammatory response, whereas a comparatively weaker affect on the energy of the affiliation between GNRI and OAB was seen for cognitive perform.
“From a clinical perspective, GNRI can be incorporated into routine screening to enhance risk stratification and inform personalized treatment strategies, potentially improving outcomes for OAB patients or those at risk of OAB,” the authors write.
Extra info:
Wei Zheng et al, Affiliation between geriatric dietary threat index and overactive bladder within the aged inhabitants: a cross-sectional research, Frontiers in Vitamin (2025). DOI: 10.3389/fnut.2025.1537549
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