Kids with newly recognized celiac illness have elevated arsenic publicity shortly after transitioning to a gluten-free eating regimen, in line with a examine printed within the April problem of the American Journal of Gastroenterology.
Nan Du, M.D., M.P.H., from Boston Kids’s Hospital, and colleagues examined adjustments in urinary arsenic focus between endoscopy and after six months on a gluten-free eating regimen amongst youngsters (aged 2 to 18 years) with elevated celiac serology. The evaluation included 35 youngsters with a biopsy diagnostic of celiac illness.
The researchers discovered that after six months of a gluten-free eating regimen, there was a big enhance within the median urinary arsenic focus (3.3 versus 13.6 µg/L). In regression fashions, after six months of a gluten-free eating regimen, household historical past of celiac illness and Hispanic ethnicity have been related to having a better urinary arsenic focus.
“Although children with newly diagnosed celiac disease had significantly increased urinary arsenic levels six months after transitioning to a gluten-free diet, measured levels were well below the threshold deemed toxic for acute exposure,” the authors write.
“The clinical effects of chronic exposure to arsenic levels of the magnitude seen in this study remain to be determined. The increase in arsenic levels observed in this cohort was likely driven by increased consumption of rice on a gluten-free diet.”
One creator disclosed ties to pharmaceutical firms.
Extra info:
Nan Du et al, Impact of Adopting a Gluten-Free Food regimen on Publicity to Arsenic and Different Heavy Metals in Kids With Celiac Illness: A Potential Cohort Examine, American Journal of Gastroenterology (2024). DOI: 10.14309/ajg.0000000000003117
Tracey M. DaFonte et al, Arsenic Publicity in Celiac Illness: The Hidden Price of a Gluten-Free Food regimen, American Journal of Gastroenterology (2024). DOI: 10.14309/ajg.0000000000003203
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Gluten-free eating regimen for celiac illness discovered to extend arsenic publicity in youngsters (2025, Could 2)
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