Hashish use dysfunction (CUD) is related to elevated threat of benign salivary gland tumors, in keeping with a analysis letter revealed on-line July 17 in JAMA Otolaryngology-Head & Neck Surgical procedure.
Tyler J. Gallagher, M.D., M.P.H., from the Keck College of Drugs on the College of Southern California in Los Angeles, and colleagues carried out a retrospective cohort examine utilizing deidentified information from the TriNetX U.S. Collaborative Community to look at the affiliation between hashish use and benign salivary gland tumors. Two cohorts of adults age 18 years or older have been created: one had a analysis of cannabis-related dysfunction and the opposite had no cannabis-related dysfunction analysis between Jan. 24, 2005, and Jan. 24, 2025.
The researchers discovered that the incidence of any benign main salivary gland tumor was larger within the group with CUD (183,818 people) than the group with out CUD (6,248,964 people) (0.08% versus 0.02%). The group with versus with out CUD additionally had larger incidence of benign parotid salivary gland tumors (0.05% versus 0.01%).
After propensity rating matching, the relative threat of any benign main salivary gland tumor was larger amongst these with versus with out CUD in any respect time factors (relative dangers, 5.18, 4.32, and 5.00 at any time, zero to lower than 5 years, and at 5 or extra years, respectively) after CUD analysis or outpatient hospital go to. Elevated relative threat of a benign parotid salivary gland tumor was additionally seen (relative dangers, 5.16, 4.92, and three.90 for any time, zero to lower than 5 years, and 5 or extra years, respectively).
“The elevated relative risk of benign parotid tumors and the persistent association over time highlight potential site-specific outcomes of cannabis use,” the authors write.
Extra data:
Tyler J. Gallagher et al, Hashish Use and Benign Salivary Gland Neoplasms, JAMA Otolaryngology–Head & Neck Surgical procedure (2025). DOI: 10.1001/jamaoto.2025.1955
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Hashish use dysfunction could up threat of benign salivary gland tumors (2025, July 21)
retrieved 21 July 2025
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