We collect cookies to analyze our website traffic and performance; we never collect any personal data. Cookie Policy
Accept
NEW YORK DAWN™NEW YORK DAWN™NEW YORK DAWN™
Notification Show More
Font ResizerAa
  • Home
  • Trending
  • New York
  • World
  • Politics
  • Business
    • Business
    • Economy
    • Real Estate
  • Crypto & NFTs
  • Tech
  • Lifestyle
    • Lifestyle
    • Food
    • Travel
    • Fashion
    • Art
  • Health
  • Sports
  • Entertainment
Reading: Hormone FGF21 discovered to affect mind’s meals reward system in response to protein restriction
Share
Font ResizerAa
NEW YORK DAWN™NEW YORK DAWN™
Search
  • Home
  • Trending
  • New York
  • World
  • Politics
  • Business
    • Business
    • Economy
    • Real Estate
  • Crypto & NFTs
  • Tech
  • Lifestyle
    • Lifestyle
    • Food
    • Travel
    • Fashion
    • Art
  • Health
  • Sports
  • Entertainment
Follow US
NEW YORK DAWN™ > Blog > Health > Hormone FGF21 discovered to affect mind’s meals reward system in response to protein restriction
Hormone FGF21 discovered to affect mind’s meals reward system in response to protein restriction
Health

Hormone FGF21 discovered to affect mind’s meals reward system in response to protein restriction

Last updated: February 26, 2025 10:13 am
Editorial Board Published February 26, 2025
Share
SHARE

Protein restriction will increase choice and motivation for whey protein in WT however not Fgf21-KO mice. Credit score: Molecular Metabolism (2024). DOI: 10.1016/j.molmet.2024.102068

When confronted with a number of meals choices and finally selecting one, the components of that decision-making course of could also be extra physiological than beforehand assumed. A bunch of scientists led by Pennington Biomedical Analysis Middle’s Dr. Christopher Morrison has found that the hormone fibroblast progress issue 21 (FGF21) performs an influential function in mind reward mechanisms like these concerned in dietary selections.

The invention was introduced within the analysis staff’s latest paper titled “FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling,” which was revealed in Molecular Metabolism. The research knowledge signifies that the FGF21 hormone acts on the mind to induce a protein-specific urge for food by enhancing the reward worth of meals that include protein.

“What’s fascinating is that this isn’t just general hunger—it’s a very specific appetite for protein,” mentioned Dr. Morrison, Affiliate Govt Director of Primary Science at Pennington Biomedical.

“When protein is restricted, FGF21 acts in the brain to flip a molecular switch that makes protein-rich foods more rewarding and motivates animals to seek them out. Many people struggle to maintain a balanced diet. Understanding how the body naturally regulates protein appetite could lead to better strategies for promoting healthy eating.”

Within the research, animals on a low-protein weight loss program labored particularly laborious for liquid protein rewards, however not carbohydrate, fatty, or candy rewards, in comparison with these on a traditional weight loss program. Nevertheless, if FGF21’s potential to behave within the mind was disrupted, this protein-specific motivation was misplaced.

The researchers then used a classy neuroscience approach referred to as fiber photometry to evaluate how vitamins activate dopamine neurons inside the ventral tegmental space, or VTA, a mind area related to reward. They found that protein restriction shifts the dopamine response, with carbohydrate extra strongly activating dopamine neurons in management animals and protein extra strongly activating dopamine neurons in protein-restricted animals. Importantly, this shift in reward signaling was misplaced in animals missing FGF21.

“It’s a remarkable example of how hormone signals can tune the brain’s reward system to drive specific nutritional appetites,” explains Dr. Morrison.

“This recent discovery demonstrates the continual journey to uncover the functions of certain genes, proteins and nutrients in our bodies while also highlighting the principal value that Pennington Biomedical delivers to the broader scientific community,” mentioned Dr. John Kirwan, Govt Director of Pennington Biomedical.

“Understanding how the brain drives specific nutritional preferences has been a long-standing challenge in metabolism research. This work exemplifies how Pennington Biomedical’s integrative approach—combining molecular biology, neuroscience, and behavioral studies—can unlock complex biological mysteries. I commend Dr. Morrison and his team for this extensive study, and I look forward to the additional discoveries that will emerge because of this one.”

The FGF21 hormone is produced within the liver and has been beforehand acknowledged as a regulator of vitality stability and for its function in glucose metabolism. This newly revealed analysis emphasizes its important affect on the central nervous system.

Extra info:
Md Shahjalal H. Khan et al, FGF21 acts within the mind to drive macronutrient-specific adjustments in behavioral motivation and mind reward signaling, Molecular Metabolism (2024). DOI: 10.1016/j.molmet.2024.102068

Offered by
Pennington Biomedical Analysis Middle

Quotation:
Hormone FGF21 discovered to affect mind’s meals reward system in response to protein restriction (2025, February 26)
retrieved 26 February 2025
from https://medicalxpress.com/information/2025-02-hormone-fgf21-brain-food-reward.html

This doc is topic to copyright. Other than any truthful dealing for the aim of personal research or analysis, no
half could also be reproduced with out the written permission. The content material is offered for info functions solely.

You Might Also Like

A shared 5 biomarker profile throughout 4 main neurodegenerative ailments

Paper-based machine detects immune defects in 10 minutes with excessive accuracy

Genetic check predicts weight problems in childhood

How precisely are racial minorities represented in US most cancers registration methods?

World research hyperlinks early smartphone possession with poorer psychological well being in younger adults

TAGGED:brainsFGF21FoodhormoneinfluenceProteinresponserestrictionRewardsystem
Share This Article
Facebook Twitter Email Print

Follow US

Find US on Social Medias
FacebookLike
TwitterFollow
YoutubeSubscribe
TelegramFollow
Popular News
Nvidia launches totally open supply transcription AI mannequin Parakeet-TDT-0.6B-V2 on Hugging Face
Technology

Nvidia launches totally open supply transcription AI mannequin Parakeet-TDT-0.6B-V2 on Hugging Face

Editorial Board May 5, 2025
Rivian’s Electric Truck Is a Cutie and a Beast
What It Was Like to Work for Russian State Television
Devcom will launch management summit with Shawn Layden and extra in Lisbon
Canadian lady arrested in $70K Taylor Swift ticket rip-off

You Might Also Like

Potty strain: 1 in 5 mother and father report struggles with rest room coaching
Health

Potty strain: 1 in 5 mother and father report struggles with rest room coaching

July 21, 2025
Single-food ‘mono diets’: Are they efficient, pointless, or simply plain harmful?
Health

Single-food ‘mono diets’: Are they efficient, pointless, or simply plain harmful?

July 20, 2025
Bitter melon for diabetes? Fenugreek for ldl cholesterol? The analysis behind historical treatments
Health

Bitter melon for diabetes? Fenugreek for ldl cholesterol? The analysis behind historical treatments

July 20, 2025
Intercourse schooling in England to incorporate warnings about choking—what mother and father must know
Health

Intercourse schooling in England to incorporate warnings about choking—what mother and father must know

July 20, 2025

Categories

  • Health
  • Sports
  • Politics
  • Entertainment
  • Technology
  • World
  • Art

About US

New York Dawn is a proud and integral publication of the Enspirers News Group, embodying the values of journalistic integrity and excellence.
Company
  • About Us
  • Newsroom Policies & Standards
  • Diversity & Inclusion
  • Careers
  • Media & Community Relations
  • Accessibility Statement
Contact Us
  • Contact Us
  • Contact Customer Care
  • Advertise
  • Licensing & Syndication
  • Request a Correction
  • Contact the Newsroom
  • Send a News Tip
  • Report a Vulnerability
Term of Use
  • Digital Products Terms of Sale
  • Terms of Service
  • Privacy Policy
  • Cookie Settings
  • Submissions & Discussion Policy
  • RSS Terms of Service
  • Ad Choices
© 2024 New York Dawn. All Rights Reserved.
Welcome Back!

Sign in to your account

Lost your password?