MM machine used to ship low-dose PEMF. The machine measures 50 cm (W) × 60 cm (L) × 110 cm (H), with a therapy chamber with an inner diameter of 26 cm and a depth of fifty cm. Credit score: Journal of Scientific Drugs (2025). DOI: 10.3390/jcm14186413
Researchers from Singapore Common Hospital (SGH) and Nationwide College of Singapore (NUS) discovered that utilizing pulsed electromagnetic fields to stimulate muscle tissue and mimic the results of train may benefit sufferers with kind 2 diabetes with extra stomach fats.
The noninvasive therapy, often called magnetic mitohormesis, prompts the identical metabolic pathways that train would usually set off. This mimics endurance train and should enhance glucose management, with out the bodily strains of train.
“We (doctors) often tell patients with diabetes to exercise because it helps control blood sugar, but we found that most people (over eight out of 10 in our study) do not exercise regularly. Many of our patients cannot do so easily due to age, health problems, or other barriers. This treatment could give similar benefits to exercise without having to work out physically,” mentioned Dr. Tan Hong Chang, Senior Marketing consultant, Division of Endocrinology, Singapore Common Hospital, and the examine’s senior writer.
The exploratory examine involving 40 adults with poorly managed kind 2 diabetes was performed at SGH from June 2023 to January 2024. Throughout every go to, every affected person’s leg is positioned right into a particular chamber machine that delivers a delicate magnetic subject to stimulate the leg muscle tissues for 10 minutes. This therapy continued weekly over 12 weeks, and not one of the individuals skilled any negative effects.
Whereas there was no important enchancment in diabetes management for all individuals, researchers found a differential response in sufferers with extra stomach fats or central weight problems. Almost 90% of sufferers on this group skilled improved blood glucose management, and their HbA1c, a key indicator of diabetes management, decreased considerably from 7.5% to 7.1% over a 3-month interval.
The researchers consider sufferers with central weight problems might reply higher as a result of they have a tendency to have muscle tissues which have poorer mobile operate and dangerous fat of their blood. Since this magnetic therapy works by gently “exercising” the muscle tissues at a mobile stage, folks with cells which might be extra “out of shape” have extra room for enchancment.
The examine findings had been revealed within the Journal of Scientific Drugs in September 2025.
This analysis represents a major step towards personalised diabetes care, significantly for the rising inhabitants of sufferers with kind 2 diabetes who battle with standard train suggestions. Nevertheless, whereas these preliminary outcomes are promising, bigger, randomized managed trials are wanted earlier than the therapy will be broadly applied.
“The NUS team has pioneered the novel use of magnetic pulses to trigger lasting physiological changes—without drugs, genetic modification, or surgery. Our early research has shown potential across areas such as health enhancement, sustainable food production, and medical therapy,” mentioned Professor Alfredo Franco-Obregón from the Institute for Well being Innovation & Know-how at NUS and the Division of Surgical procedure in NUS Yong Lavatory Lin Faculty of Drugs, and the examine’s corresponding writer.
“Notably, the findings of this clinical study—conducted in partnership with SGH—aligns with our previous preclinical and clinical work showing that fat tissue responds very well to the magnetic muscle treatment, helping to lower inflammation and potentially driving better health outcomes,” he added.
SGH and NUS researchers are taking a look at future research that may give attention to figuring out optimum therapy length and frequency and figuring out which affected person profiles profit most.
Extra info:
Fan Shuen Tseng et al, Investigating the Metabolic Advantages of Magnetic Mitohormesis in Sufferers with Kind 2 Diabetes Mellitus, Journal of Scientific Drugs (2025). DOI: 10.3390/jcm14186413
Quotation:
Magnetic subject remedy exhibits promise in mimicking train advantages for kind 2 diabetes sufferers with central weight problems (2025, October 31)
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