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People who find themselves older than 80 ought to be thought-about for osteoporosis remedy after a fracture to keep away from additional danger, in accordance with a research being offered Saturday at ENDO 2025, the Endocrine Society’s annual assembly in San Francisco, Calif.
“The burden of osteoporosis is rising as the global population ages rapidly,” mentioned Gianina Flocco, M.D., a resident on the Cleveland Clinic in Cleveland, Ohio. “Our study supports the initiation of osteoporosis treatment after a fracture in people older than 80 years, as it has been shown to decrease both hospitalization and mortality.”
Flocco and colleagues used the TriNextX well being analysis database to review 88,676 sufferers aged 80 and older who suffered a fracture on account of bone deterioration or weak spot brought on by osteoporosis.
The sufferers have been segmented into two teams. The primary included 44,338 sufferers who have been handled with bisphosphonates, denosumab, raloxifene or teriparatide. The second group had the identical variety of sufferers, however included those that did not obtain any osteoporosis therapies.
Sufferers have been adopted for five years after the preliminary fracture. The analysis accounted for comorbidities, together with hypertension, diabetes, ischemic coronary heart illness, weight problems, coronary heart failure, stroke, COPD, persistent kidney illness, hyperlipidemia, rheumatoid arthritis, neoplasm and vitamin D deficiency.
The sufferers within the remedy group skilled a decrease danger of hospitalization. This group additionally skilled decrease all-cause mortality.
Flocco mentioned that the burden of osteoporosis is predicted to extend sooner or later. These research outcomes assist their suggestion to deal with older sufferers who’re most weak to fractures as they proceed to age.
“The results of our study support the need to enhance the individualized initiation of treatment of osteoporosis, even in people who are older than 80,” she mentioned. “Treating people to reduce the burden of osteoporosis complications, like fractures leading to disability or death, would play a significant role in improving health span in the growing older population.”
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The Endocrine Society
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Osteoporosis remedy may benefit folks older than 80 (2025, July 12)
retrieved 12 July 2025
from https://medicalxpress.com/information/2025-07-osteoporosis-treatment-benefit-people-older.html
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