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In sufferers of reproductive age who’ve most cancers, fertility preservation for potential youngsters sooner or later ought to be a excessive precedence. A apply article revealed within the Canadian Medical Affiliation Journal describes the profitable preservation of ovarian tissue in a younger lady present process pressing chemotherapy and demonstrates a novel mannequin of look after Canada.
“This case illustrates the complex challenges faced by young patients with cancer who desire biological children but require urgent treatment that threatens their reproductive potential,” writes Dr. Jennia Michaeli, a fertility specialist at Mount Sinai Hospital, a part of Sinai Well being, and clinician–investigator and assistant professor on the College of Toronto, Toronto, Ontario, with co-authors.
“Unfortunately, many life-saving interventions—including reproductive organ surgery, chemotherapy, and abdominopelvic radiation—increase the risk of infertility and reproductive endocrine dysfunction.”
The affected person, positioned 380 km from Toronto, determined to endure ovarian tissue preservation after being endorsed on choices, the dangers of surgical procedure, and steps within the process.
The fertility staff at Mount Sinai in Toronto coordinated care remotely with the affected person’s native oncologist and gynecologist to make sure the tissue was eliminated surgically, then transported underneath steady temperature management to a specialised embryology lab at Mount Sinai.
Regardless of Canadian tips endorsing fertility preservation as a regular of look after sufferers with most cancers, affected person misery round survival, an absence of doctor data of choices, and restricted capability within the system pose limitations to wider adoption of the apply.
This affected person’s case reveals that implementing a centralized “hub-and-spoke” mannequin may assist open the doorways to ovarian tissue cryopreservation for younger sufferers with most cancers throughout Canada.
“We successfully delivered specialized oncofertility services through coordinated care pathways that overcame geographical barriers, which serves as a proof of concept,” write the authors.
“The described model aims to reduce infertility and reproductive endocrine dysfunction, minimize the psychosocial impact of infertility, and enhance the quality of life for patients and their families by improving access and coordination of care.”
Extra data:
Fertility preservation by ovarian tissue transportation and centralized cryobanking for a 20-year-old lady with Hodgkin lymphoma, Canadian Medical Affiliation Journal (2025). DOI: 10.1503/cmaj.250519
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Canadian Medical Affiliation Journal
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Ovarian tissue preservation allows future fertility for younger lady with most cancers (2025, November 17)
retrieved 17 November 2025
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