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Ozone (O3) publicity could scale back the supply of oxygen within the physique, leading to arterial stiffening as a result of physique’s pure response to create extra crimson blood cells and hemoglobin, based on a research revealed within the Journal of the American School of Cardiology (JACC).
“Researchers found that even brief exposure to elevated ozone levels reduced blood oxygen saturation, triggered hypoxia-related biomarkers, and increased arterial stiffness, highlighting the novel connection between ozone exposure and arterial stiffness, demonstrated through comprehensive biomarker analysis in a high-altitude setting,” mentioned Dr. Harlan Krumholz, MD, SM, Editor-in-Chief of JACC.
“This study uniquely isolates ozone’s effects from other pollutants, providing a critical step forward in understanding its independent role in cardiovascular injury.”
Ozone air pollution is changing into a worldwide well being subject. Current research have linked O3 publicity with an elevated danger of cardiovascular ailments (CVDs), together with ischemic coronary heart illness, stroke, coronary heart failure, and atherosclerosis. Hypoxia, or the deficiency of oxygen within the physique, is acknowledged as a pivotal think about O3-associated CVDs.
Extra data:
Associations of Brief-Time period Ozone Publicity With Hypoxia and Arterial Stiffness, Journal of the American School of Cardiology (2025). DOI: 10.1016/j.jacc.2024.11.044
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American School of Cardiology
Quotation:
Ozone publicity linked to hypoxia and arterial stiffness (2025, January 22)
retrieved 22 January 2025
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