Postmenopausal girls, notably those that expertise early menopause, could have a better danger for creating rheumatoid arthritis (RA), in response to a overview revealed on-line Sept. 30 in BMC Rheumatology.
Negin Namavari, M.D., from the Faculty of Drugs at Peymaniye Hospital and the Jahrom College of Medical Science in Iran, and colleagues performed a scientific literature overview and meta-analysis to evaluate the affiliation between menopause and RA. Eleven research had been included within the meta-analysis.
The researchers discovered that postmenopausal girls had a better danger for creating RA versus premenopausal girls (odds ratio, 1.35). Ladies who skilled early menopause (earlier than 45 years of age) confirmed considerably increased odds of creating RA than those that underwent menopause at a standard age (odds ratio, 2.97).
“These findings underscore the importance of menopausal status as a potential risk factor for RA, with the substantial increase in RA risk associated with early menopause warranting particular attention from both clinicians and researchers,” the authors write.
“Our results suggest several avenues for future research, including investigation into the biological mechanisms underlying the association between menopause and RA risk, development of targeted preventive strategies for postmenopausal women (especially those who experience early menopause), and exploration of potential interventions to mitigate RA risk in these higher-risk groups.”
Extra data:
Negin Namavari et al, Menopausal state and rheumatoid arthritis: a scientific overview and meta-analysis, BMC Rheumatology (2024). DOI: 10.1186/s41927-024-00418-2
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Postmenopausal girls discovered to have increased danger for creating rheumatoid arthritis (2024, December 18)
retrieved 19 December 2024
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