For asymptomatic rheumatoid arthritis (RA) sufferers, a brand new radiation-free screening protocol can determine suspected interstitial lung involvement (ILI), based on a examine printed on-line Nov. 23 in BMC Pulmonary Drugs.
Frank Reichenberger, M.D., from Augustinum Hospital Munich, and colleagues proposed a noninvasive, radiation-free strategy to ILI screening utilizing pulmonary perform exams (PFT) and pleuro-pulmonary transthoracic ultrasound (LUS) with further cardiopulmonary train exams with electrocardiography and echocardiography.
The examine included 67 consecutive sufferers with a confirmed analysis of seropositive RA, with out signs for or recognized heart problems. When vital LUS abnormalities and extra PFT modifications have been current, interstitial lung illness (ILD) was suspected.
The researchers discovered that 40% of sufferers had noticeable modifications in LUS, 24% with a sample appropriate with ILD. LUS abnormalities and extra PFT modifications have been current in 16% of circumstances, and ILI was suspected. Obstructive lung illness; subpleural consolidation, together with one confirmed lung most cancers; minimal pleural effusion; and ischemic cardiac illness have been included as further findings (11, six, six, and two sufferers, respectively). Pulmonary vascular involvement was not seen in any of the sufferers.
“Our study supports the growing evidence and experience in using LUS for screening for RA-ILD,” the authors write. “We propose LUS as an appropriate imaging tool in combination with PFT for ILD screening in RA.”
Extra info:
Frank Reichenberger et al, Proposal of a radiation-free screening protocol for early detection of interstitial lung involvement in seropositive and ACPA-positive rheumatoid arthritis, BMC Pulmonary Drugs (2024). DOI: 10.1186/s12890-024-03405-y
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Radiation-free screening can determine interstitial lung involvement in rheumatoid arthritis (2024, December 6)
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