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A brand new research led by researchers at Moffitt Most cancers Heart exhibits that asymptomatic mind metastasis is extra frequent in stage 4 breast most cancers sufferers than beforehand believed. The research, revealed in Neuro-Oncology, means that medical doctors might must rethink present screening pointers for detecting mind metastasis in sufferers with out signs.
Researchers examined 101 asymptomatic sufferers identified with stage 4 breast most cancers, together with triple-negative, HER2-positive and hormone receptor-positive/HER2-negative breast most cancers. These sufferers underwent MRI scans to test for mind metastasis, with a follow-up MRI six months later if the preliminary scan confirmed no indicators of most cancers unfold.
Of the sufferers who accomplished the preliminary MRI, 14% had mind metastasis. The charges by subtype had been:
“Our study suggests that asymptomatic brain metastasis is quite common in stage 4 breast cancer,” mentioned Kamran Ahmed, M.D., affiliate member and part chief for Breast Radiation Oncology at Moffitt and principal investigator of the research. “Although larger studies are needed to confirm our findings, given the improvements in systemic and local therapies for breast cancer brain metastasis, the time may be appropriate to reconsider current guidelines that recommend against routine MRI surveillance in late stage breast cancer.”
Extra info:
Kamran A Ahmed et al, Part II Trial of Mind MRI Surveillance in Stage IV Breast Most cancers, Neuro-Oncology (2025). DOI: 10.1093/neuonc/noaf018
Supplied by
H. Lee Moffitt Most cancers Heart & Analysis Institute
Quotation:
Research helps routine mind MRI screening in asymptomatic late-stage breast most cancers sufferers (2025, January 28)
retrieved 28 January 2025
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