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Researchers at Memorial Sloan Kettering Most cancers Middle (MSK) have reported outcomes from the first-ever medical trial demonstrating {that a} high-fiber, plant-based dietary intervention might delay development to a number of myeloma, a uncommon and incurable blood most cancers affecting the bone marrow.
The research enrolled 20 contributors with a precancerous blood dysfunction and an elevated physique mass index (BMI) liable to creating a number of myeloma. They acquired 12 weeks of excessive fiber plant-based meals and 24 weeks of teaching. Two contributors with progressing illness previous to the research confirmed a big enchancment of their illness development trajectory. Moreover, at one 12 months after enrollment, not one of the contributors had progressed to a number of myeloma. MSK myeloma specialist and NUTRIVENTION research lead, Urvi Shah, MD, introduced these findings on the 2024 American Society of Hematology (ASH) annual assembly in San Diego, California.
“This study showcases the power of nutrition—specifically a high fiber plant-based diet—and unlocks a better understanding of how it can lead to improvements in the microbiome and metabolism to build a stronger immune system,” mentioned Dr. Shah. “These findings further support how we as physicians can empower patients, especially those with precancerous conditions, with knowledge on reducing their cancer risk through dietary changes.”
A number of myeloma is the second commonest blood most cancers and usually arises from precursor situations known as monoclonal gammopathy of undetermined significance (MGUS) and smoldering (symptomless) myeloma. Latest research have proven an elevated danger of a number of myeloma in people with poor high quality of food regimen and decreased consumption of plant meals. Moreover, people with these situations and an elevated physique mass index (BMI) are twice as prone to progress to a number of myeloma as folks with these situations and a traditional BMI. With this data, researchers have been on the lookout for methods to intervene earlier than these situations can progress to most cancers.
These findings had been confirmed in a smoldering myeloma mouse mannequin the place 44% of mice fed the excessive fiber food regimen didn’t progress to myeloma in comparison with the usual food regimen the place all mice progressed to myeloma.
Extra data:
671 A Excessive-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Issues Improves Biomarkers of Illness and Might Delay Development to Myeloma, ash.confex.com/ash/2024/webpro … ram/Paper202224.html
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Memorial Sloan Kettering Most cancers Middle
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Research hyperlinks high-fiber food regimen to delayed development of blood most cancers (2024, December 8)
retrieved 8 December 2024
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