Respiratory syncytial virus (RSV) is related to a substantial burden of hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths amongst adults, based on a research printed on-line Nov. 13 in JAMA Community Open.
Utilizing information from the RSV Hospitalization Surveillance Community, Fiona P. Havers, M.D., from the U.S. Facilities for Illness Management and Prevention in Atlanta, and colleagues describe the demographic traits and outcomes of adults hospitalized with laboratory-confirmed RSV in 58 counties in 12 states. Seven surveillance seasons had been included, from 2016–2017 by means of 2022–2023.
The researchers discovered there have been 16,575 RSV-associated hospitalizations in adults in the course of the surveillance interval. Excluding the 2020–2021 and 2021–2022 seasons, when RSV circulation was affected by COVID-19, hospitalization charges different from 48.9 to 76.2 per 100,000 adults in 2016–2017 and 2017–2018, respectively.
The bottom charges had been seen amongst adults aged 18 to 49 years (8.6 to 13.1 per 100,000 adults in 2016–2017 and 2022–2023, respectively), and the best charges had been seen for these aged 75 years or older (244.7 to 411.4 per 100,000 adults in 2022–2023 and 2017–2018, respectively). There was variation famous within the annual hospitalization estimates, from 123,000 to 193,000 in 2016–2017 and 2017–2018, respectively.
For a similar seasons, the annual ICU admission estimates different from 24,400 to 34,900. There was additionally variation seen in estimated annual in-hospital deaths, from 4,680 to eight,620 in 2018–2019 and 2017–2018, respectively. Adults aged 75 years or older accounted for 45.6, 38.6, and 58.7% of all RSV-associated hospitalizations, ICU admissions, and in-hospital deaths, respectively.
“Increasing vaccine coverage among adults at highest risk could reduce associated hospitalizations and severe clinical outcomes,” the authors write.
Extra data:
Fiona P. Havers et al, Burden of Respiratory Syncytial Virus–Related Hospitalizations in US Adults, October 2016 to September 2023, JAMA Community Open (2024). DOI: 10.1001/jamanetworkopen.2024.44756
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