Acquired Immune Deficiency Syndrome

Why Monkeypox Vaccine Shortage May Threaten the Immunocompromised

The shortfall of monkeypox vaccine doses in the United States, expected to last for months, is raising urgent questions about how well and for how long a single shot may protect against the virus. The vaccine, called Jynneos, is approved as a two-dose regimen, but most people at risk of infection have been receiving one […]

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H.I.V. Infections Remain Persistently High, U.N. Reports

While the world’s attention was riveted on the Covid pandemic and the war in Ukraine, the fight against an older foe lost crucial ground: More than 1.5 million people became infected with H.I.V. last year, roughly three times the global target, the United Nations reported on Wednesday. Roughly 650,000 people died of AIDS in 2021, […]

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As Poor Nations Seek Covid Pills, Officials Fear Repeat of AIDS Crisis

The cost to UNICEF of Paxlovid — including Pfizer’s insistence that UNICEF keep how much it pays confidential — remains a sticking point, said Dr. Philippe Duneton, who runs the therapeutics arm of the W.H.O. consortium. In announcing its “strong recommendation” for Paxlovid, the W.H.O. took the highly unusual step of publicly scolding Pfizer for […]

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The Secrets Ed Koch Carried

Edward I. Koch looked like the busiest septuagenarian in New York. Glad-handing well-wishers at his favorite restaurants, gesticulating through television interviews long after his three terms as mayor, Mr. Koch could seem as though he was scrambling to fill every hour with bustle. He dragged friends to the movies, pursuing a side career in film […]

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A Woman Is Cured of H.I.V. Using a Novel Treatment

A bone marrow transplant is not a realistic option for most patients. Such transplants are highly invasive and risky, so they are generally offered only to people with cancer who have exhausted all other options. There have only been two known cases of an H.I.V. cure so far. Referred to as “The Berlin Patient,” Timothy […]

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How The mRNA Vaccines Were Made: Halting Progress and Happy Accidents

“I said, ‘I am an RNA scientist. I can do anything with RNA,’” Dr. Karikó recalled telling Dr. Weissman. He asked her: Could you make an H.I.V. vaccine? “Oh yeah, oh yeah, I can do it,” Dr. Karikó said. Up to that point, commercial vaccines had carried modified viruses or pieces of them into the […]

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In South Africa, Success Against H.I.V. Offers Hope

Back then, I reported from villages in Eswatini, then known as Swaziland, where I couldn’t find more than a handful of people my age — just children and elderly people. I wrote from Johannesburg about the day that Nelson Mandela broke a powerful taboo and told South Africans his son had died of AIDS. I […]

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