Clinical Trials
Officials Wrestle With Whether to Allow New Monkeypox Vaccination Strategy
WASHINGTON — It sounded like a simple solution to the shortage of monkeypox vaccine: Merely by changing the way doses are injected, the federal government could vaccinate five times as many people with the supply it has in hand. But the approach — injecting one-fifth of the current dose into the skin instead of a […]
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Why Monkeypox Vaccine Shortage May Threaten the Immunocompromised
The shortfall of monkeypox vaccine doses in the United States, expected to last for months, is raising urgent questions about how well and for how long a single shot may protect against the virus. The vaccine, called Jynneos, is approved as a two-dose regimen, but most people at risk of infection have been receiving one […]
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Vitamin D Supplements Don’t Help Another Condition, Study Finds
The idea made so much sense it was almost unquestioningly accepted: Vitamin D pills can protect bones from fractures. After all, the body needs the vitamin for the gut to absorb calcium, which bones need to grow and stay healthy. But now, in the first large randomized controlled study in the United States, funded by […]
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Covid-19 Vaccines Temporarily Changed Menstrual Cycles, Study Shows
Nearly half of the participants of a recent study who were menstruating regularly at the time of the survey reported heavier bleeding during their periods after receiving the Covid-19 vaccine. Others who did not typically menstruate — including transgender men, people on long-acting contraceptives, and post-menopausal women — also experienced unusual bleeding. The new study […]
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Cancer Drug Greatly Reduces Deaths in Hospitalized Covid Patients
An experimental drug initially developed to fight cancer cut the risk of death for people hospitalized with Covid by half, according to a study published on Wednesday. The drug, sabizabulin, seemed to be more effective than others that have been authorized for severely ill Covid patients. Veru, the company in Miami that developed the drug, […]
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Are Covid Vaccines That Defend Against Omicron Variants Too Late?
Roseann Renouf, 77, has grown tired of the current generation of coronavirus shots. Having “never been one for a lot of vaccination,” she decided to forgo the latest round of boosters after watching vaccinated friends contract Covid-19, even though the doses offer a critical extra layer of protection. “It’s just taking another same booster,” Ms. […]
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After Six-Decade Hiatus, Experimental Psychedelic Therapy Returns to the V.A.
The Department of Veterans Affairs recently began offering psychedelic substances to patients as a part of clinical trials, a major step in the quest to determine the therapeutic potential of illegal drugs the federal government has long deemed dangerous. At least five trials are underway or being planned by a handful of government clinicians who […]
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A Better Way to Measure Immunity in Children
For Jacqueline Almeida, next week cannot come soon enough. She has watched friends roll their eyes when she asked to meet them outdoors. She has tried unsuccessfully to convince her sister to vaccinate her son. She was told by strangers on Twitter that putting her daughter in a mask was tantamount to child abuse. And […]
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F.D.A. Panel Recommends Pfizer and Moderna Vaccines for Youngest Children
WASHINGTON — The only Americans still not eligible for coronavirus vaccines — babies, toddlers and preschoolers — appear on the verge of finally getting cleared to receive them after an advisory panel to the Food and Drug Administration voted unanimously on Wednesday to recommend the Pfizer and Moderna vaccines for the group. The F.D.A. appears […]
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