Schematic illustration of the organic capabilities of nutritional vitamins and minerals and their major dietary sources. Credit score: Knowledgeable Assessment of Anticancer Remedy (2025). DOI: 10.1080/14737140.2025.2501077
A brand new examine coordinated by Dr. Salvatore Cortellino and Professor Antonio Giordano, President of the Sbarro Well being Analysis Group (SHRO) and molecular oncologist at Temple College and the College of Siena, gives a essential evaluation of vitamin supplementation and fashionable dietary traits within the context of most cancers prevention and remedy.
Revealed in Knowledgeable Assessment of Anticancer Remedy, the assessment cautions towards the widespread perception, promoted by mass media and the wellness business, that over-the-counter nutritional vitamins and fad diets can independently lengthen life expectancy or enhance most cancers outcomes.
This work has been considerably enhanced by the esteemed contributions of Teresa Esposito, MD, Division of Medical Dietetics and Metabolic Ailments, Cavalier Raffaele Apicella Hospital, ASL Napoli 3 Sud, Naples, Italy, and Francesca Pentimalli, Ph.D., Division of Drugs and Surgical procedure, LUM College “Giuseppe De Gennaro,” Bari, Italy.
The evaluation reveals that whereas vitamin deficiencies are incessantly noticed in most cancers sufferers and will contribute to elevated most cancers danger, supplementation via pharmaceutical-grade multivitamins has not demonstrated clear scientific profit. As an alternative, the authors underscore the significance of a balanced weight loss program, significantly the Mediterranean weight loss program, as probably the most dependable technique for sustaining ample micronutrient ranges.
Crucially, the assessment raises issues about hypervitaminosis, a situation ensuing from extreme consumption of nutritional vitamins with out medical supervision. In oncological sufferers, such an imbalance might paradoxically stimulate tumor development. Likewise, dietary traits equivalent to ketogenic regimens, intermittent fasting, and even strict veganism, whereas supported by preclinical fashions, lack sturdy proof of effectiveness in human most cancers remedy. In some instances, these restrictive dietary practices might exacerbate cancer-related cachexia or lead to malnutrition, significantly in frail or aged sufferers.
“Our findings suggest that following dietary fashions without clinical guidance can be not only ineffective but potentially harmful for cancer patients,” explains Professor Giordano. “There is no substitute for evidence-based medicine and a personalized approach to nutrition.”
The authors advocate for medical session earlier than initiating any important dietary change, particularly within the presence of danger elements or energetic illness. Dietary choices, whether or not associated to dietary supplements or complete consuming plans, must be made in collaboration with certified well being care professionals equivalent to physicians, scientific nutritionists, or dietitians.
The examine concludes by reaffirming that well being is greatest preserved via physiological stability, achieved by sustaining ample caloric consumption, adhering to a diversified and healthful weight loss program, and interesting in common bodily exercise in accordance with particular person wants. These ideas, rooted within the European Code Towards Most cancers and the Mediterranean way of life, stay the cornerstone of most cancers prevention and affected person well-being.
Extra data:
Teresa Esposito et al, Nutritional vitamins and dietary dietary supplements in most cancers remedy: is there a necessity for elevated utilization? Knowledgeable Assessment of Anticancer Remedy (2025). DOI: 10.1080/14737140.2025.2501077
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Sbarro Well being Analysis Group (SHRO)
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Vitamin dietary supplements and most cancers: New examine warns towards unsupervised dietary interventions (2025, Might 12)
retrieved 12 Might 2025
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