Credit score: CC0 Public Area
Three research offered at this time on the Society of NeuroInterventional Surgical procedure’s (SNIS) twenty second Annual Assembly mentioned whether or not utilizing GLP-1 inhibitors might reduce the affect of stroke and associated mind accidents or cut back the chance of stroke altogether. These medicines, which decrease blood sugar and sometimes trigger weight reduction, are generally prescribed for sort 2 diabetes and weight problems and embody medicine like semaglutide (Ozempic).
Within the first examine, “The Impact of Semaglutide (Ozempic) on Mortality and Survival in Patients with Acute Ischemic Stroke: A Nationwide and Institutional Retrospective Analysis,” researchers on the College of Wisconsin–Madison used affected person information from each the college’s medical middle and a worldwide well being collaborative to see whether or not sufferers on Ozempic who skilled strokes had higher outcomes than sufferers not taking Ozempic.
The worldwide dataset included 2,021,704 sufferers who had skilled stroke, 43,338 of whom have been additionally on Ozempic, and the College of Wisconsin dataset included 13,510 individuals who had skilled stroke, 190 of whom used Ozempic. Loss of life from stroke was decrease for Ozempic customers throughout each cohorts.
Within the international dataset, 5.26% of Ozempic customers initially died from their strokes in comparison with 21.61% of non-users, and Ozempic customers additionally had a 77.5% probability of surviving their strokes in the long run in comparison with 30.95% of non-Ozempic customers. The college cohort confirmed comparable outcomes, with 5.26% of Ozempic customers dying from stroke versus 26.57% of sufferers not utilizing Ozempic.
Within the second examine, additionally from the College of Wisconsin–Madison, “Association between Ozempic Use and Stroke Risk: A Nationwide Emergency Department Analysis,” researchers examined a big nationwide pattern of emergency division information for individuals who skilled stroke and individuals who have been probably utilizing Ozempic. They discovered associations between potential Ozempic customers and considerably diminished odds of stroke. The analysis workforce suggests taking this analysis additional to guage information instantly from pharmacies to be much more exact concerning the relationship between Ozempic and stroke prevention.
The third examine, “Impact of GLP-1 Agonists on Stroke, SAH, and ICH: A Propensity-matched Multi-institutional Cohort Study,” was offered by researchers from the College of Texas Medical Department in Galveston. They investigated whether or not GLP-1 inhibitors might enhance affected person outcomes after mind hemorrhages (each spontaneous bleeds and people as a result of mind aneurysm rupture) and stroke.
The workforce reviewed affected person information from 6 months and 12 months after every mind hemorrhage and 1 yr and a couple of years after every stroke, discovering that GLP-1 inhibitor use was related to a diminished danger of cognitive uncomfortable side effects, seizures, future mind hemorrhage and dying after mind hemorrhage and stroke.
In accordance with Ahmed Elbayomy, MD, a analysis fellow and information scientist within the Division of Neurological Surgical procedure on the College of Wisconsin–Madison and first creator of two of those research, these outcomes are very promising.
“More research is certainly needed, but seeing the potential protection offered by these medications is a fascinating finding,” says Elbayomy.
“This research could introduce a new perspective to the discussion of preventing and mitigating the devastating effects of stroke and related brain injuries,” added Matias Costa, MD, from the Neurosurgery Division on the College of Texas Medical Department and creator of the third examine.
Supplied by
Society of NeuroInterventional Surgical procedure
Quotation:
Weight reduction medicine like Ozempic could assist stop stroke and cut back mind injury-related problems, research present (2025, July 17)
retrieved 17 July 2025
from https://medicalxpress.com/information/2025-07-weight-loss-drugs-ozempic-brain.html
This doc is topic to copyright. Other than any truthful dealing for the aim of personal examine or analysis, no
half could also be reproduced with out the written permission. The content material is supplied for info functions solely.
