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New analysis reveals that the quantity and complexity of most cancers scientific trials since 2001 have assorted throughout low- and middle-income international locations (LMICs), with financial development contributing to disparities, however solely to a sure extent. The findings are revealed in Most cancers.
Though LMICs are anticipated to expertise the best world burden of most cancers within the coming years, most cancers scientific trials are disproportionately concentrated in high-income international locations. As a result of proof means that LMICs have elevated the variety of most cancers scientific trials over the previous couple of many years, researchers investigated disparities within the quantity and complexity of such trials amongst LMICs over time and in response to financial modifications.
Between 2001 and 2020, a complete of 16,977 most cancers scientific trials in LMICs had been registered. The Asian international locations of China and South Korea skilled robust financial development and will increase in scientific trials. Comparable developments, although much less spectacular, had been noticed in East European international locations and the West Asian/Southern European nation of Turkey.
Conversely, South and Southeast Asian international locations like India, Thailand, and Vietnam—which additionally skilled robust financial development—had primarily inconsistent development in scientific trials.
The North and South American international locations of Argentina, Brazil, and Mexico had been capable of enhance their variety of scientific trials regardless of relative financial stagnation.
Amongst African international locations, Egypt confirmed robust financial development with a corresponding enhance in scientific trials, however no such correlation was seen in South Africa.
Taken collectively, the findings recommend that financial development is a contributor however not the one determinant of most cancers scientific trial development amongst LMICs.
“We believe these data offer valuable insights for LMICs aiming to enhance clinical research,” mentioned senior writer Max S. Mano, MD, Ph.D., of the Latin American Cooperative Oncology Group and Einstein Hospital Israelita, in Brazil.
Extra data:
Disparities in Most cancers Medical Trials Amongst Low- and Center-income International locations: a 20-year Evaluation, Most cancers (2025). DOI: 10.1002/cncr.70067
Quotation:
What’s the extent of disparities in most cancers scientific trials amongst low- and middle-income international locations? (2025, October 20)
retrieved 20 October 2025
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