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The Swedish Nationwide Affected person Register (NPR) has lengthy been a cornerstone for epidemiological analysis. Researchers at Karolinska Institutet have revealed a brand new assessment analyzing the validity of the register and located that it’s good for many diagnoses and excellent for surgical procedures.
A earlier assessment was carried out in 2010 however solely included inpatient care. The brand new assessment additionally consists of specialised outpatient care, offering a extra full image of the validity of the NPR.
Revealed within the European Journal of Epidemiology, the researchers carried out systematic searches in medical databases and picked up studies from members of the Swedish Epidemiological Affiliation to determine all research validating diagnoses and process codes in inpatient care since 2010 and all research validating specialised outpatient care. Moreover, outcomes from register validation work carried out by the Nationwide Board of Well being and Welfare are summarized.
“Our review shows that the Swedish National Patient Register has good diagnostic accuracy for most diagnoses and very good accuracy for surgical procedures, but with significant variability in PPV and sensitivity depending on diagnosis, coding definitions, reference standards, and data sources,” says Åsa Everhov, Docent on the Division of Medication Solna and the primary writer of the article.
The register has develop into extra full over time. The diploma of underreporting is at present low, though it’s larger amongst non-public well being care suppliers and for particular variables equivalent to drug administration.
“Longitudinal comparisons of incidence or prevalence are affected by changes in completeness. It is important that researchers are aware of these limitations when using the NPR for their studies,” says Ola Olén, the final writer of the research and Professor on the Division of Medication Solna.
The assessment emphasizes the worth of the NPR whereas highlighting limitations to make sure it stays an essential useful resource for epidemiological analysis each in Sweden and internationally.
Extra info:
Åsa H. Everhov et al, Diagnostic accuracy within the Swedish nationwide affected person register: a assessment together with diagnoses within the outpatient register, European Journal of Epidemiology (2025). DOI: 10.1007/s10654-025-01221-0
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Karolinska Institutet
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Good diagnostic accuracy present in Swedish Nationwide Affected person Register (2025, April 4)
retrieved 4 April 2025
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