Greater calcium consumption is related to diminished colorectal most cancers (CRC) danger throughout tumor websites and calcium sources, in keeping with a examine revealed on-line Feb. 17 in JAMA Community Open.
Semi Zouiouich, Ph.D., M.P.H., from the Nationwide Most cancers Institute in Bethesda, Maryland, and colleagues examined the affiliation between calcium consumption and CRC danger in a cohort examine analyzing information from the Nationwide Institutes of Well being-AARP Food regimen and Well being Research involving individuals aged 50 to 71 years at baseline (October 1995 to Might 1996) with self-reported good well being and neither extraordinarily excessive nor low caloric or calcium consumption.
The researchers recognized 10,618 first major CRC instances throughout 7,339,055 person-years of follow-up amongst 471,396 individuals who had been cancer-free at baseline. Imply whole calcium consumption for the bottom quintile (Q1) was 401 mg/d for ladies and 407 mg/d for males; imply whole consumption for the best quintile (Q5) was 2,056 mg/d for ladies and 1,773 mg/d for males.
A decrease danger for CRC was seen in affiliation with larger whole calcium consumption (Q5 versus Q1: hazard ratio, 0.71; 95% confidence interval, 0.65 to 0.78; P
“While calcium intake may vary by race and ethnicity, the potential for calcium to play a role in CRC prevention appeared to be consistent across racial and ethnic groups; still, research in racial and ethnic minority populations is needed,” the authors write.
Extra data:
Semi Zouiouich et al, Calcium Consumption and Threat of Colorectal Most cancers within the NIH-AARP Food regimen and Well being Research, JAMA Community Open (2025). DOI: 10.1001/jamanetworkopen.2024.60283
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